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Occasional digestive upset can occur even in long-term users, typically triggered by dietary indiscretions, stress, or other factors unrelated to the medication
Patients with diabetes should also seek help if they have symptoms that could suggest dangerously high or low blood sugar
Clinical trials show patients typically achieve clinically significant weight reduction with semaglutide or tirzepatide over 12-18 months without mandated exercise, though individual results vary based on medication adherence, dosing, dietary patterns, and baseline characteristics
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A Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 Diabetes (PIONEER 12)
